Varr Miranda, A.; Talavera De la Esperanza, B.; Mart ez P s, E.; Trigo L ez, J.; G ez L ez de San Rom , C.; Ruiz Pi ro, M.; Pedraza Hueso, M.I.; Guerrero Peral, L.; Garc Azor , D The Journal of Headache and Discomfort 2017, 18(Suppl 1):POBJECTIVE: The very first trigeminal nerve branch is divided in 3 most important branches: lacrimal nerve (LN), frontal nerve, which divides into supraorbital (SON) and supratrochlear nerves and nasociliar nerve. We describe the case of a Tricaine Cancer patient diagnosed of supraorbital nerve neuralgia who created an ipsilateral lacrimal neuralgia. PATIENT AND Solutions: 47-year-old lady with prior health-related history of Crohn disease treated with Adalimumab and Azatioprine. She complained about a oppressive continuous discomfort, of 510 intensity as outlined by Analogic Visual Scale circumscribed for the left supraciliar region, with 2-3 seconds length superimposed paroxysms of 810 intensity. In the physical examination we detected tenderness in the palpation of your supraorbital notch. She was treated by anesthetic lidocaine blockade successfully and was managed in the course of 6 years with blockades every single 3-10 months. Benefits: In a typical seek the advice of she complained of a brand new oppressive discomfort of 610 intensity inside the left superoexternal periorbital region, with three seconds stabbing paroxisms of 810 intensity. Inside the exam she presented pain in the palpation of lacrimal nerve and circumscribed hypoesthesia within the lacrimal nerve territory. We only performed SON blockade very first but the superoexternal pain persisted, so we performed a particular lacrimal nerve blockade with pain cessation, confirming the diagnosis of Lacrimal Neuralgia. A facial, orbital and cranial CT did not show any PYBG-TMR MedChemExpress abnormality. CONCLUSSION: Sequential presentation of pain in contiguous nervous branches inside the absence of structural lesions supports the epicranial nature of the trigeminal terminal branches neuralgias. Consent for publication: The authors declare that written informed consent was obtained for publication. P8 Cognitive impairment in episodic and chronic migraineurs and tension-type headache suffers A. Bianchi, R. Monastero, M. Dav F. Brighina, C. Camarda Division of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Italy Correspondence: A. Bianchi ([email protected]) The Journal of Headache and Discomfort 2017, 18(Suppl 1):P8 Background. Migraine and tension-type headache are hugely prevalent brain disorders characterized by recurrent painful attacks that lead to a extremely disabling condition, especially when chronic. Headache suffers regularly reported cognitive deficits, nonetheless previously information concerning cognitive impairment are inconclusive. The aim of this hospital-based study was to compare cognitive performance in subjects impacted by different headache types such as: migraine with no aura (MWA), chronic migraine (CM), tension type headache (TTH) and chronic tension kind headache (CTTH). Materials and procedures. We studied 307 patients, 246 lady and 61 male consecutively referred for the Adult Headache Centre, Neurological Unit from the University of Palermo through a 2-year period. Headache diagnoses were established as outlined by the ICHD-III criteria. Each patient carried out a complete neuropsychological evaluation including: MiniMental State Examination (MMSE), Rey Auditory Verbal Studying Test (episodic memory), Token Test (verbal comprehension), Frontal Assessment Battery (executive functioning), and Visual Search (selective attention).