The JmjC domain-containing histone lysine demethylases (JmjC KDMs) represent a large superfamily of enzymes that catalyze oxidative demethylation of methylated lysine residues on histones using Fe(II) and 2-oxoglutarate as cofactors.…
Neonatal brain injury remains a leading cause of long-term neurodevelopmental disability, with conditions such as hypoxic-ischemic encephalopathy (HIE), intracranial hemorrhage, congenital heart disease, and severe prematurity posing significant risks. Early…
The development of clusteroluminogenic materials from heteroatom-rich small molecules represents a paradigm shift in the design of sustainable luminescent systems. This work demonstrates how structurally simple, nonaromatic heterocycles—specifically maleimide and…
The performance of proton exchange membranes (PEMs) hinges critically on their atomic-level structure and the chemical environment governing ion transport. In this study, we conducted a comprehensive structural and functional…
The adsorption capacity of microplastics (MPs) for heavy metals is primarily governed by surface characteristics, among which crystallinity and functional group composition play pivotal roles. This study examined the influence…
Nicotinamide adenine dinucleotide phosphate (NAD(P)H) is a central redox cofactor essential for cellular energy metabolism, biosynthesis, and redox homeostasis. Its dynamic fluctuations are closely linked to physiological and pathological processes,…
Diffusion-weighted MRI (DW-MRI) of the abdomen, particularly the kidneys, offers non-invasive assessment of tissue microstructure through quantitative parameters such as apparent diffusion coefficient (ADC), fractional anisotropy (FA), and intravoxel incoherent…
This study presents a high-performance microfluidic separator that utilizes multi-modal ultrasonic standing waves to achieve efficient, continuous fractionation of microparticles based on size differences. The device is designed to overcome…
The University of Washington has been at the forefront of advancing organic light emitting diodes (OLEDs), transforming fundamental research into high-performance, commercially relevant technologies. Since the early 2000s, UW researchers…
The development of biodegradable fibrous scaffolds via electrospinning has emerged as a critical strategy in tissue engineering, offering tunable microarchitectures that closely mimic the natural extracellular matrix. This study investigates…