Name :
MAP2K4 (Human) Recombinant Protein
Biological Activity :
Human MAP2K4 (NP_003001.1, 1 a.a. – 399 a.a.) full-length recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Full-Length Protein,Full-Length Proteins,Full-Length,Full Length,FullLength
Tag :
Result of activity analysis
Protein Accession No. :
NP_003001.1
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=6416
Amino Acid Sequence :
Molecular Weight :
71
Storage and Stability :
Store at -80°C.Aliquot to avoid repeated freezing and thawing.
Host :
insect
Interspecies Antigen Sequence :
Preparation Method :
Baculovirus infected insect cell (Sf21) expression system
Purification :
Glutathione sepharose chromatography
Quality Control Testing :
Loading 1 ug protein in SDS-PAGE
Storage Buffer :
In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
Applications :
Functional Study， SDS-PAGE，
Gene Name :
MAP2K4
Gene Alias :
JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SEK1, SERK1
Gene Description :
mitogen-activated protein kinase kinase 4
Gene Summary :
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq
Other Designations :
JNK activating kinase 1|JNK-activated kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|dual specificity mitogen-activated protein kinase kinase 4
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